Nucleated red blood cells: Immune cell mediators of the antiviral response
نویسندگان
چکیده
منابع مشابه
Piscine birnavirus triggers antiviral immune response in trout red blood cells, despite not being infective.
Background: Some fish viruses, such as piscine orthoreovirus and infectious salmon anemia virus, target red blood cells (RBCs), highly replicate inside them and induce an immune response. However, the implications of RBCs in the context of birnavirus infection (i.e, infectious pancreatic necrosis virus (IPNV)) have not yet been studied. Methods:Ex vivo trout RBCs were obtained from peripheral b...
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Although nucleated red blood cells (nRBCs) are rarely found circulating in older children, they are commonly seen in the blood of newborns. They are primarily produced in the fetal bone marrow in response to erythropoietin and are stored in the marrow as precursors to reticulocytes and mature erythrocytes. Many acute and chronic stimuli cause increases in the number of circulating nRBCs from ei...
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Background: Early diagnosis is paramount to the treatment of neonatal infections. Nucleated red blood cells (NRBCs) are immature erythrocytes that increase in number due to stress and hypoxia. This study was conducted to determine NRBC count in the peripheral blood and examine its significance as a marker of neonatal infection. Methods: This case-control study was conducted on 154 infants (78 ...
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OBJECTIVE The purpose of this study was to evaluate whether the absolute nucleated red blood cell and lymphocyte count is elevated in term, appropriate-for-gestational-age infants born to women with asthma. STUDY DESIGN We compared absolute nucleated red blood cell counts taken during the first 12 hours of life in two groups of term, vaginally delivered, appropriate-for-gestational-age infant...
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The D antigen content of nucleated red cell precursors in human bone marrow was estimated using autoradiography and 125I-anti-D. D antigen first appeared in the pronormoblast, and the quantity of antigen progressively increased during red cell maturation. Maximal anti-D binding occurred on mature red blood cells. Pronormoblasts, basophilic normoblasts, polychromatophilic normoblasts, and orthoc...
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ژورنال
عنوان ژورنال: PLOS Pathogens
سال: 2018
ISSN: 1553-7374
DOI: 10.1371/journal.ppat.1006910